| No | Size | Price | Availability | |
| ARP4205-11 | 50ul | 1500.00 | In Stock |  |
| ARP4205-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4205 |
| Isotype: | / | Swiss Prot: | Q02078 |
| purity: | Affinity purification |
| Background: |
| The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 54 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:50-1:100
|
| Immunogen | A synthetic peptide corresponding to residues surrounding T312 of human MEF2A |
| Storage | Store at -20°C in PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | ADCAD1, RSRFC4, RSRFC9 |
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