| No | Size | Price | Availability | |
| ARP26585-11 | 50ul | 1500.00 | In Stock |  |
| ARP26585-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 26585 |
| Isotype: | / | Swiss Prot: | O60565 |
| purity: | Protein G purification |
| Background: |
| This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. [provided by RefSeq |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 21 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:50-1:100
|
| Immunogen | A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GREM1 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2, MGC126660, PIG2 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
