| Source: | Rabbit | Gene Id: | 59272 |
| Isotype: | / | Swiss Prot: | Q9BYF1 |
| purity: | Protein G purification |
| Background: |
| The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB IHC ELISA FC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 120-135 kDa |
| Recommended Dilutions |
WB 1:50-1:200
IHC 1:50-1:100
FC 1:10-1:50
|
| Immunogen | A synthetic peptide (conjugated with KLH) corresponding to internal region of human ACE2 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | ACEH, DKFZp434A014 |
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