Source: | Rabbit | Gene Id: | 26524 |
Isotype: | / | Swiss Prot: | Q9NRM7 |
purity: | Protein G purification |
Background: |
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB IHC ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 150 kDa |
Recommended Dilutions |
WB 1:100-1:500
IHC 1:10-1:50
|
Immunogen | A synthetic peptide (conjugated with KLH) corresponding to amino acids 195-224 at internal region of human LATS2 |
Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
Synonym | FLJ13161, KPM |
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