METAP2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP10988-12 50ul 1500.00 In Stock
ARP10988-12 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 10988
Isotype: / Swiss Prot: P50579
purity: Protein G purification
Background:
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq
Reactivity Human
Tested applications IHC ELISA
Clonality Polyclonal Antibody
Calculated MW 63 kDa
Recommended Dilutions
IHC 1:10-1:50
Immunogen A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human METAP2
Storage Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles.
Synonym MAP2, MNPEP, p67, p67eIF2
This product is for research use only, not for diagnostic or therapeutic use!

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