Source: | Rabbit | Gene Id: | 10988 |
Isotype: | / | Swiss Prot: | P50579 |
purity: | Protein G purification |
Background: |
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq |
Reactivity | Human |
Tested applications | IHC ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 63 kDa |
Recommended Dilutions |
IHC 1:10-1:50
|
Immunogen | A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human METAP2 |
Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
Synonym | MAP2, MNPEP, p67, p67eIF2 |
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