| No | Size | Price | Availability | |
| ARP5979-11 | 50ul | 1500.00 | In Stock |  |
| ARP5979-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5979 |
| Isotype: | / | Swiss Prot: | P07949 |
| purity: | Protein G purification |
| Background: |
| This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 170,175 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:50-1:100
|
| Immunogen | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human RET |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | CDHF12, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51 |
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