| No | Size | Price | Availability | |
| ARP23092-11 | 50ul | 1500.00 | In Stock |  |
| ARP23092-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 23092 |
| Isotype: | / | Swiss Prot: | Q9UNA1 |
| purity: | Protein G purification |
| Background: |
| GTPase Regulator Associated with Focal Adhesion Kinase-1 (GRAF1), is a GTPase-activating protein for the small G proteins RhoA and Cdc42 (1). It is composed of an N-terminal BAR domain, a PH domain, a RhoGAP domain, a proline-rich domain, and a C-terminal SH3 domain. GRAF1 contributes to the clathrin-independent carriers/GPI-enriched early endosomal compartments (CLIC/GEEC) pathway, and was the first specific protein component of this endocytic pathway to be discovered (2). GRAF1 was identified as an important protein necessary for adeno-associated virus 2 infection (3). In addition, research studies have linked GRAF1 to mental retardation (4), skeletal muscle differentiation (5), and myeloid leukemia (6,7). |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 92 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:50-1:100
|
| Immunogen | A synthetic peptide (conjugated with KLH) corresponding to internal region of human ARHGAP26 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | FLJ42530, GRAF, KIAA0621, OPHN1L, OPHN1L1 |
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