| No | Size | Price | Availability | |
| ARP5923-11 | 50ul | 1500.00 | In Stock |  |
| ARP5923-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5923 |
| Isotype: | / | Swiss Prot: | Q13972 |
| purity: | Protein A purification |
| Background: |
| The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 130 kDa |
| Recommended Dilutions |
WB 1:50-1:100
IHC 1:10-1:50
|
| Immunogen | A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S929 of human RASGRF1 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187 |
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