| No | Size | Price | Availability | |
| ARP4905-11 | 50ul | 1500.00 | In Stock |  |
| ARP4905-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4905 |
| Isotype: | IgG | Swiss Prot: | P46459 |
| purity: | Antigen affinity purification |
| Background: |
| Several protein-protein interactions are essential to membrane fusion during endocytosis. Membrane fusion requires interaction among SNARE1 proteins associated with both donor and acceptor membranes (1,2). Following membrane fusion, the α-SNAP cytoplasmic adapter protein binds to the SNARE complex. N-ethylmaleimide-sensitive factor (NSF), a hexameric ATPase, then associates with the α-SNAP/SNARE complex to mediate SNARE disassembly during membrane fusion (3,4). The ATPase activity of NSF induces a conformational change in the α-SNAP/SNARE complex that leads to its dissociation from the membrane, membrane fusion and eventual recycling of the SNARE complex for subsequent membrane fusion (3,4). |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 78 kDa |
| Recommended Dilutions |
WB 1:100-1:250
IHC 1:50-1:200
IF 1-4 ug/mL
|
| Immunogen | A recombinant protein corresponding to amino acids of human NSF |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | SKD2 |
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