| No | Size | Price | Availability | |
| ARP2316-11 | 50ul | 1500.00 | In Stock |  |
| ARP2316-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2316 |
| Isotype: | IgG | Swiss Prot: | P21333 |
| purity: | Antigen affinity purification |
| Background: |
| The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 280 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:200-1:500
IF 1-4 ug/mL
|
| Immunogen | A recombinant protein corresponding to amino acids of human FLNA |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | ABP-280, ABPX, DKFZp434P031, FLN, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2 |
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