| No | Size | Price | Availability | |
| ARP10509-11 | 50ul | 1500.00 | In Stock |  |
| ARP10509-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10509 |
| Isotype: | / | Swiss Prot: | J3KNP4 |
| purity: | Immunoaffinity chromatography |
| Background: |
| The semaphorin family of proteins is involved in axon guidance, cell migration, angiogenesis, and immune response. Plexins and neuropilins bind with high affinity to semaphorins to mediate their functions. Semaphorins are divided into seven classes of secreted or membrane-bound proteins. Members of Class 4 semaphorins include 4A through 4G; semaphorin 4B is a membrane-associated protein (1,2). Semaphorin 4B binds to the CLCP1 receptor and regulates cell motility (3). Furthermore, semaphorin 4B, like many other semaphorins, has a PDZ domain-binding motif at the carboxy terminus that interacts with PSD95 and localizes to the post-synaptic membrane (4). |
| Reactivity | Human |
| Tested applications | IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 105 kDa |
| Recommended Dilutions |
IHC 10-15 ug/mL
|
| Immunogen | A synthetic peptide corresponding to 16 amino acids at N-terminus region of human SEMA4B |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.1% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | KIAA1745, MGC131831, SEMAC, SemC |
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