Source: | Goat | Gene Id: | 7137 |
Isotype: | / | Swiss Prot: | P19429 |
purity: | Antigen affinity purification |
Background: |
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq |
Reactivity | Chiken, Dog, Human |
Tested applications | WB ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 27 kDa |
Recommended Dilutions |
WB 1-3 ug/mL
|
Immunogen | A synthetic peptide corresponding to human TNNI3 |
Storage | Store at 4°C. For long term storage store at -20°C in Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA).Avoid freeze/thaw cycles. |
Synonym | CMD2A, CMH7, MGC116817, RCM1, TNNC1, cTnI |
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