Source: | Rabbit | Gene Id: | 1051 |
Isotype: | / | Swiss Prot: | P17676 |
purity: | Antigen affinity purification |
Background: |
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 35-49 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide corresponding to human CEBPB |
Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.2 (15 mM sodium azide).Avoid freeze/thaw cycles. |
Synonym | C/EBP-beta, CRP2, IL6DBP, LAP, MGC32080, NF-IL6, TCF5 |
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