Source: | Rabbit | Gene Id: | 26354 |
Isotype: | / | Swiss Prot: | Q9BVP2 |
purity: | Ammonium sulfate precipitation |
Background: |
Nucleostemin (GNL3) is a member of the MMR1/HSR1 GTP-binding protein family. It is essential in early embryogenesis (1) and investigators have shown that nucleostemin participates in the control of stem and cancer cell cycle proliferation (2), possibly through regulation of p53 activity (3). Nucleostemin has been found to be expressed in CNS stem cells, embryonic stem cells, and several cancer cell lines, and is localized to both the nucleus and the nucleolus in a cell-cycle dependent manner (4). |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 65 kDa |
Recommended Dilutions |
WB 1:50-1:100
IHC 1:10-1:50
|
Immunogen | A synthetic peptide (conjugated with KLH) corresponding to amino acids 465-495 at C-terminus of humanGNL3 |
Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.09% sodium azide).Avoid freeze/thaw cycles. |
Synonym | C77032, E2IG3, MGC800, NS |
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