| No | Size | Price | Availability | |
| ARP408P-11 | 50ul | 1500.00 | In Stock |  |
| ARP408P-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 408 |
| Isotype: | / | Swiss Prot: | P49407 |
| purity: | Antigen affinity purification |
| Background: |
| Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding S412 of ARRB1 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.2 (15 mM sodium azide).Avoid freeze/thaw cycles. |
| Synonym | ARB1, ARR1 |
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