| Source: | Rabbit | Gene Id: | 706 | 
| Isotype: | IgG | Swiss Prot: | P30536 | 
| purity: | Antigen affinity purification | 
| Background: | 
| Translocator protein (TSPO) is an 18 kDa mitochondrial drug- and cholesterol-transporting protein involved in steroid hormone synthesis and mitochondrial homeostasis in a variety of cell types (1,2). Originally thought to play a role exclusively in steroid synthesis in steroidogenic cells, subsequent research studies have implicated TSPO in a variety of pathologies in a broad range of tissues including progression of breast cancer, neuroinflammation, and neurological disorders (1,3-5). TSPO was first identified by its ability to bind benzodiazepines in peripheral tissues and glial cells, hence its alternate name Peripheral Benzodiazepine Receptor (PBR). | 
| Reactivity | Human | 
| Tested applications | IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 18 kDa | 
| Recommended Dilutions | 
                                    
                                     IHC 1:200-1:500 
                                    
                                    
                                    
                                    
                                    
                                 | 
                            
| Immunogen | A recombinant protein corresponding to amino acids of human ZNF706 | 
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. | 
| Synonym | HSPC038, PNAS-106, PNAS-113 | 
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