Source: | Rabbit | Gene Id: | 706 |
Isotype: | IgG | Swiss Prot: | P30536 |
purity: | Antigen affinity purification |
Background: |
Translocator protein (TSPO) is an 18 kDa mitochondrial drug- and cholesterol-transporting protein involved in steroid hormone synthesis and mitochondrial homeostasis in a variety of cell types (1,2). Originally thought to play a role exclusively in steroid synthesis in steroidogenic cells, subsequent research studies have implicated TSPO in a variety of pathologies in a broad range of tissues including progression of breast cancer, neuroinflammation, and neurological disorders (1,3-5). TSPO was first identified by its ability to bind benzodiazepines in peripheral tissues and glial cells, hence its alternate name Peripheral Benzodiazepine Receptor (PBR). |
Reactivity | Human |
Tested applications | IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 18 kDa |
Recommended Dilutions |
IHC 1:200-1:500
|
Immunogen | A recombinant protein corresponding to amino acids of human ZNF706 |
Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
Synonym | HSPC038, PNAS-106, PNAS-113 |
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