| No | Size | Price | Availability | |
| ARP51247-11 | 50ul | 1500.00 | In Stock |  |
| ARP51247-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 51247 |
| Isotype: | IgG | Swiss Prot: | Q9BPZ3 |
| purity: | Antigen affinity purification |
| Background: |
| The eukaryotic mRNA 3' poly(A) tail interacts with the 5' cap structure to regulate translation of mRNA transcripts (1). The eIF4G translation initiation factor associates with poly(A) binding protein (PABP) to circularize mRNA (1,2). Paip1 is a PABP interacting protein that binds eIF4A to stimulate translation (3). A second PABP binding protein, Paip2, inhibits translation by interfering with PABP function. Specifically, Paip2 reduces the affinity of PABP for poly(A) RNA and competes with Paip1 for PABP binding (1,2). |
| Reactivity | Human |
| Tested applications | IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 25 kDa |
| Recommended Dilutions |
IHC 1:200-1:500
|
| Immunogen | A recombinant protein corresponding to amino acids of human PAIP2 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | MGC72018, PAIP2A |
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