| No | Size | Price | Availability | |
| ARP6319-11 | 50ul | 1500.00 | In Stock |  |
| ARP6319-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6319 |
| Isotype: | IgG | Swiss Prot: | O00767 |
| purity: | Antigen affinity purification |
| Background: |
| Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5 (MIM 608370), have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Zhang et al. (1999) [PubMed 10229681]; Wang et al., 2005 [PubMed 15907797]).[supplied by OMIM |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 37 kDa |
| Recommended Dilutions |
WB 1:250-1:500
IHC 1:50-1:200
IF 1-4 ug/mL
|
| Immunogen | A recombinant protein corresponding to amino acids of human SCD |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | FADS5, MSTP008, SCD1 |
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