| No | Size | Price | Availability | |
| ARP64332-11 | 50ul | 1500.00 | In Stock |  |
| ARP64332-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 64332 |
| Isotype: | IgG | Swiss Prot: | Q9BYH8 |
| purity: | Antigen affinity purification |
| Background: |
| The NF-κB/Rel transcription factors are present in the cytosol in an inactive state complexed with the inhibitory IκB proteins (1-3). Activation occurs via phosphorylation of IκBα at Ser32 and Ser36 followed by proteasome-mediated degradation that results in the release and nuclear translocation of active NF-κB (3-7). IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. Kinases that phosphorylate IκB at these activating sites have been identified (8). |
| Reactivity | Human |
| Tested applications | IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 85 kDa |
| Recommended Dilutions |
IHC 1:20-1:50
|
| Immunogen | A recombinant protein corresponding to amino acids of human KIAA0907 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | RP11-336K24.1 |
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