CD2AP Rabbit Polyclonal Antibody
No Size Price Availability  
ARP23607-12 50ul 1500.00 In Stock
ARP23607-12 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 23607
Isotype: / Swiss Prot: Q9Y5K6
purity: Antigen affinity purification
Background:
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 130 kDa
Recommended Dilutions
WB 1:250-1:500
IHC 1:200-1:500
IF 1-4 ug/mL
Immunogen A recombinant protein corresponding to amino acids of human CD2AP
Storage Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles.
Synonym CMS, DKFZp586H0519
This product is for research use only, not for diagnostic or therapeutic use!

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