| No | Size | Price | Availability | |
| ARP55004-11 | 50ul | 1500.00 | In Stock |  |
| ARP55004-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 55004 |
| Isotype: | / | Swiss Prot: | Q6IAA8 |
| purity: | Antigen affinity purification |
| Background: |
| mTORC1 kinase complex is a critical component in the regulation of cell growth (1,2). Its activity is modulated by energy levels, growth factors, and amino acids (3,4). The four related GTPases, RagA, RagB, RagC, and RagD, have been shown to interact with raptor in mTORC1 (1,2). These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals (1,2). A protein complex consisting of LAMTOR1/C11orf59, LAMTOR2/ROBLD3, and LAMTOR3/MAPKSP1 has been identified to interact with and recruit the four Rag GTPases to the surface of lysosomes (5). |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 18 kDa |
| Recommended Dilutions |
WB 1:250-1:500
IHC 1:200-1:500
IF 1-4 ug/mL
|
| Immunogen | A recombinant protein corresponding to amino acids of human C11orf59 |
| Storage | Store at 4°C. For long term storage store at -20°C in PBS, pH 7.5 (40% glycerol, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | FLJ20625 |
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