Source: | Goat | Gene Id: | 4644 |
Isotype: | / | Swiss Prot: | Q9Y4I1 |
purity: | Affinity purification |
Background: |
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB ELISA IF |
Clonality | Polyclonal Antibody |
Calculated MW | 210 kDa |
Recommended Dilutions |
WB 1-3 ug/mL
IF 1-3 ug/mL
|
Immunogen | A synthetic peptide corresponding to amino acids at internal region of human MYO5A |
Storage | Store at -20°C in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide).Avoid freeze/thaw cycles. |
Synonym | GS1, MYH12, MYO5, MYR12 |
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