| No | Size | Price | Availability | |
| ARP837-11 | 50ul | 1500.00 | In Stock |  |
| ARP837-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 837 |
| Isotype: | / | Swiss Prot: | P49662 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 45 kDa |
| Recommended Dilutions |
WB 1:200-1:1000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide corresponding to 14 amino acids of human CASP4 |
| Storage | Store at 4°C for three months. For long term storage store at -20°C in buffer containing 0.02% sodium azide.Avoid freeze/thaw cycles. |
| Synonym | ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX |
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