Source: | Rabbit | Gene Id: | 51360 |
Isotype: | / | Swiss Prot: | O43462 |
purity: | Affinity purification |
Background: |
This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response |
Reactivity | Human, Mouse, Rat |
Tested applications | IF ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 57 kDa |
Recommended Dilutions |
IF 1:500-1:1000
|
Immunogen | A synthetic peptide corresponding to internal of human MBTPS2 |
Storage | Store at -20°C in PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol).Avoid freeze/thaw cycles. |
Synonym | FLJ32174, S2P |
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