Source: | Rabbit | Gene Id: | 1387 |
Isotype: | / | Swiss Prot: | Q92793 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB IHC ELISA IF |
Clonality | Polyclonal Antibody |
Calculated MW | 300 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
IF 1:500-1:1000
|
Immunogen | A synthetic peptide corresponding to N-terminus of human DOK7 |
Storage | Store at -20°C in PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol).Avoid freeze/thaw cycles. |
Synonym | C4orf25, Dok-7, FLJ33718, FLJ39137, FLJ90556 |
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