Phospho-PDGFRB-Tyr1021 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5159P-13 50ul 1500.00 In Stock
ARP5159P-13 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5159
Isotype: / Swiss Prot: P09619
purity: Affinity purification
Background:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq
Reactivity Human
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 190 kDa
Recommended Dilutions
WB 1:5000
Immunogen A synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1021 of human PDGFRB
Storage Store at -20°C in HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).
Synonym CD140B, JTK12, PDGF-R-beta, PDGFR, PDGFR1
This product is for research use only, not for diagnostic or therapeutic use!

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