| No | Size | Price | Availability | |
| ARP6786-12 | 50ul | 1500.00 | In Stock |  |
| ARP6786-12 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6786 |
| Isotype: | / | Swiss Prot: | Q13586 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 85 kDa |
| Recommended Dilutions |
WB 1-2 ug/mL
|
| Immunogen | A synthetic peptide corresponding to C-terminus 24 amino acids of human STIM1 |
| Storage | Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | D11S4896E, GOK |
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