| No | Size | Price | Availability | |
| AGPM002N-11 | 50ul | 1500.00 | In Stock |  |
| AGPM002N-11 | 100ul | 2000.00 | In Stock | |
| Source: | Goat | Gene Id: | / |
| Isotype: | / | Swiss Prot: | / |
| purity: | Affinity purification |
| Background: |
| Nitric oxide (NO) is implicated in carcinogenesis (1), chronic infection, inflammation (2) and neurodegeneration (3). High levels of both superoxide and nitric oxide in tissues interact to form peroxynitrite, a potent oxidant that can modify Tyr residues in proteins to form 3-nitro-tyrosine (4). Tyrosine nitration of mitochondrial manganese superoxide dismutase results in loss of enzymatic activity (4). The nitration of p53 at Tyr residues abolishes its capacity for binding to its DNA consensus sequence (5). |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:5000-1:40000
|
| Immunogen | Nitrotyrosine conjugated with KLH |
| Storage | Store at 4°C. For long term storage store at -20°C n 75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, pH 7.2 (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | / |
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