SNCA/B Rabbit Polyclonal Antibody
No Size Price Availability  
ARPF003-11 50ul 1500.00 In Stock
ARPF003-11 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 6620/6622
Isotype: / Swiss Prot: Q16143/P37840
purity: Immunoaffinity purification
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
Reactivity Human
Tested applications IHC
Clonality Polyclonal Antibody
Calculated MW 18 kDa
Recommended Dilutions
IHC 1:50
Immunogen A synthetic peptide corresponding to N-terminus of human SNC
Storage Store at 4°C in 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide).
Synonym MGC110988, NACP, PARK1, PARK4, PD1
This product is for research use only, not for diagnostic or therapeutic use!

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