Source: | Goat | Gene Id: | 2893 |
Isotype: | / | Swiss Prot: | P48058 |
purity: | Affinity purification |
Background: |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 100 kDa |
Recommended Dilutions |
WB 0.3-1 ug/mL
IHC 5-10 ug/mL
|
Immunogen | A synthetic peptide corresponding to human GRIA4 |
Storage | Store at -20°C in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide).Avoid freeze/thaw cycles. |
Synonym | GLUR4, GLUR4C, GLURD |
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