Source: | Rabbit | Gene Id: | 8643 |
Isotype: | / | Swiss Prot: | Q9Y6C5 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the patched gene family. The patched protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. This gene is shown to be mutated in a medulloblastoma and in a basal cell carcinoma, suggesting that it plays a role in the development of some tumors. Alternative transcript variants have been described, but their biological function has not been determined. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 130 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide corresponding to amino acids 226-235 of human PTCH2 |
Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
Synonym | / |
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