Source: | Rabbit | Gene Id: | 9252 |
Isotype: | / | Swiss Prot: | O75582 |
purity: | Affinity purification |
Background: |
MSK1, a mitogen and stress activated protein kinase, is activated by Erk as well as p38 MAPK in response to growth factors and cellular stress, respectively (1). MSK1 resembles RSK because it has two kinase domains connected by a regulatory linker region (2). Phosphorylation of RSK1 at Ser364 and Ser381 is critical for RSK1 activity (3). These sites are analogous to Ser360 and Ser376 of MSK1, which may be important for MSK1 activity as well. |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 90 kDa |
Recommended Dilutions | |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser376 of human MSK1 |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MGC1911, MSK1, MSPK1, RLPK |
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