Phospho-PRKCQ-Thr538 Rabbit Polyclonal Antibody
| No |
Size |
Price |
Availability |
|
| ARP5588P-31 |
50ul |
1500.00 |
In Stock |
 |
| ARP5588P-31 |
100ul |
2000.00 |
In Stock |
|
| Source: |
Rabbit |
Gene Id: |
5588 |
| Isotype: |
/ |
Swiss Prot: |
Q04759 |
| purity: |
Affinity purification |
| Background: |
| Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. |
| Reactivity |
Human, Mouse, Rat |
| Tested applications |
WB |
| Clonality |
Polyclonal Antibody |
| Calculated MW |
79 kDa |
| Recommended Dilutions |
|
| Immunogen |
A synthetic phosphopeptide corresponding to residues surrounding Thr538 of human PKCtheta |
| Storage |
Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym |
MGC12651, MGC141919, PRKCT, nPKC-theta |
This product is for research use only, not for diagnostic or therapeutic use！
