Source: | Rabbit | Gene Id: | 29110 |
Isotype: | IgG | Swiss Prot: | Q9UHD2 |
purity: | Affinity purification |
Background: |
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. |
Reactivity | Human |
Tested applications | ELISA Dot |
Clonality | Polyclonal Antibody |
Calculated MW | 84 kDa |
Recommended Dilutions | |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser172 of human TBK1 |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | NAK, T2K |
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