Source: | Rabbit | Gene Id: | 5336 |
Isotype: | / | Swiss Prot: | P16885 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 150 kDa |
Recommended Dilutions | |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Tyr759 of human PLCgamma2 |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | FCAS3, APLAID, RP11-510J16.3 |
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