Source: | Rabbit | Gene Id: | 29904 |
Isotype: | / | Swiss Prot: | O00418 |
purity: | Affinity purification |
Background: |
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 105 kDa |
Recommended Dilutions | |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser366 of human eEF2k |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | eEF-2K, HSU93850 |
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