| Source: | Rabbit | Gene Id: | 1399 |
| Isotype: | / | Swiss Prot: | P46109 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 39 kDa |
| Recommended Dilutions | |
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Tyr207 of human CrkL |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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