Phospho-RB1-Ser608 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5925P-31 50ul 1500.00 In Stock
ARP5925P-31 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5925
Isotype: / Swiss Prot: P06400
purity: Affinity purification
Background:
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Reactivity Human
Tested applications IHC ELISA Dot
Clonality Polyclonal Antibody
Calculated MW 110 kDa
Recommended Dilutions
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser608 of human Rb
Storage Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Synonym RB, pRb, OSRC, pp110, p105-Rb
This product is for research use only, not for diagnostic or therapeutic use!

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