CASP4 Rabbit Polyclonal Antibody
| No |
Size |
Price |
Availability |
|
| ARP837-14 |
50ul |
1500.00 |
In Stock |
 |
| ARP837-14 |
100ul |
2000.00 |
In Stock |
|
| Source: |
Rabbit |
Gene Id: |
837 |
| Isotype: |
/ |
Swiss Prot: |
P49662 |
| purity: |
Affinity purification |
| Background: |
| This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq |
| Reactivity |
Human, Mouse |
| Tested applications |
WB IHC |
| Clonality |
Polyclonal Antibody |
| Calculated MW |
45 kDa |
| Recommended Dilutions |
WB 1 ug/mL
|
| Immunogen |
A synthetic peptide corresponding to N-terminus of human CASP4 |
| Storage |
Store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym |
ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX |
This product is for research use only, not for diagnostic or therapeutic use！
