DLG3 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP1741-11 50ul 1500.00 In Stock
ARP1741-11 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Rabbit Gene Id: 1741
Isotype: / Swiss Prot: P07858
purity: Affinity purification
Background:
This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Reactivity Human, Mouse, Rat
Tested applications WB IF
Clonality Polyclonal Antibody
Calculated MW 102 kDa
Recommended Dilutions
WB 1:1000
Immunogen A recombinant protein corresponding to SLC12A3 N-terminus (amino acids 74-95)
Storage Store at 4°C. For long term storage store at -20°C in PBS, 50% glycerol and 0.09% sodium azide.Avoid freeze/thaw cycles.
Synonym FLJ96318, NCCT, TSC
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us