Source: | Rabbit | Gene Id: | 5454 |
Isotype: | IgG | Swiss Prot: | P20265 |
purity: | Peptide affinity purification |
Background: |
POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM |
Reactivity | Human, Mouse, Rat |
Tested applications | WB ELISA |
Clonality | Polyclonal Antibody |
Calculated MW | 55 kDa |
Recommended Dilutions |
WB 1-2 ug/mL
|
Immunogen | A synthetic peptide corresponding to 18 amino acids at C-terminus of human POU3F2 |
Storage | Store at 4°C. For long term storage store at -20°C in PBS (0.05% sodium azide).Avoid freeze/thaw cycles. |
Synonym | BRN2, OCT7, OTF7, POUF3 |
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