| Source: | Rabbit | Gene Id: | 23118 |
| Isotype: | IgG1 | Swiss Prot: | Q9NYJ8 |
| purity: | Affinity Purification |
| Background: |
| The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | IHC ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 80 kDa |
| Recommended Dilutions |
IHC 5 ug/mL
|
| Immunogen | A synthetic peptide corresponding to 14 amino acids at C-terminus of human MAP3K7IP2 |
| Storage | Store at -20°C. For long term storage store at -80°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | FLJ21885, KIAA0733, TAB2 |
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