| No | Size | Price | Availability | |
| ARP4914P-11 | 50ul | 1500.00 | In Stock |  |
| ARP4914P-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4914 |
| Isotype: | / | Swiss Prot: | P04629 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IP IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 140 kDa |
| Recommended Dilutions |
WB 1 ug/mL
ICC 10-20 ug/mL
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Y490 of human NTRK1 |
| Storage | Store at -20°C. For long term storage store at -80°in PBS pH 7.2 (50% glycerol, 1% BSA, 0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | DKFZp781I14186, MTC, TRK, TRK1, TRKA, p140-TrkA |
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