Source: | Rabbit | Gene Id: | 3381 |
Isotype: | / | Swiss Prot: | P21815 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq |
Reactivity | Human, Rat |
Tested applications | WB IHC ELISA ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 82 kDa |
Recommended Dilutions |
ICC 1:100
|
Immunogen | Native purified IBSP from human bone sialoprotein |
Storage | Store at 4°C on dry atmosphere.After reconstitution with distilled water, store at -20°C or lower.Avoid freeze/thaw cycles. |
Synonym | BNSP, BSP, BSP-II, SP-II |
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