| No | Size | Price | Availability | |
| ARP54541-11 | 50ul | 1500.00 | In Stock |  |
| ARP54541-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 54541 |
| Isotype: | / | Swiss Prot: | Q9NX09 |
| purity: | Affinity purification |
| Background: |
| REDD1 (REgulated in Development and DNA damage responses) expression is induced by hypoxia, cell stress, apoptosis and DNA damage. REDD1 is a transcriptional target of p53 and p63 following DNA damage, and links p63 to Ros (1). REDD1 functions as a negative regulator of mTOR in response to hypoxia in a tuberin-dependent manner (2). Depending on cell context, REDD1 can either be protecting or detrimental for cells under oxidative or ischemic stresses (3). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 28 kDa |
| Recommended Dilutions |
WB 0.5-1 ug/mL
|
| Immunogen | A synthetic peptide corresponding to internal region 12 amino acids of human DDIT4 |
| Storage | Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | Dig2, FLJ20500, REDD-1, REDD1, RP11-442H21.1, RTP801 |
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