| No | Size | Price | Availability | |
| ARP55851-13 | 50ul | 1500.00 | In Stock |  |
| ARP55851-13 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 55851 |
| Isotype: | / | Swiss Prot: | Q9NZ42 |
| purity: | Affinity purification |
| Background: |
| Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 13 kDa |
| Recommended Dilutions |
WB 0.5-1 ug/mL
|
| Immunogen | A synthetic peptide corresponding to N-terminus 13 amino acids of human PSENEN |
| Storage | Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | MDS033, MSTP064, PEN-2, PEN2 |
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