| No | Size | Price | Availability | |
| ARP10017-11 | 50ul | 1500.00 | In Stock |  |
| ARP10017-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10017 |
| Isotype: | / | Swiss Prot: | Q9HD36 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq |
| Reactivity | Human |
| Tested applications | WB ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 23 kDa |
| Recommended Dilutions |
WB 1-2 ug/mL
|
| Immunogen | A synthetic peptide corresponding to amino acids near N-terminus of human BCL2L10 |
| Storage | Store at 4°C for three months. For long term storage store at -20°C in PBS (0.02% sodium azide).Avoid freeze/thaw cycles. |
| Synonym | BCL-B, Boo, Diva, MGC129810, MGC129811 |
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