Source: | Rabbit | Gene Id: | 8654 |
Isotype: | / | Swiss Prot: | O76074 |
purity: | Affinity purification |
Background: |
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IP |
Clonality | Polyclonal Antibody |
Calculated MW | 100 kDa |
Recommended Dilutions |
WB 1:20000
|
Immunogen | C terminal region of human PDE5A |
Storage | Store at 4°C. For long term storage store at -20°C in serum. |
Synonym | CGB-PDE, CN5A, PDE5, PDE5A1 |
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