| No | Size | Price | Availability | |
| ARP64236-12 | 50ul | 1500.00 | In Stock |  |
| ARP64236-12 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 64236 |
| Isotype: | / | Swiss Prot: | Q96JY6 |
| purity: | Affinity purification |
| Background: |
| PDLIM2, also known as Mystique, contains an amino-terminal PDZ domain and a carboxy-terminal LIM domain. PDLIM2 was orginally found to be associated with cytoskeletal proteins in epithelial cells to promote cell attachment and migration. Subsequent studies have shown that PDLIM2 can also inhibit NF-κB activity by acting as a nuclear ubiquitin E3 ligase for p65. PDLIM2 is suppressed in cancer cell lines by DNA methylation. Expression of PDLIM2 can inhibit anchorage-independent growth and tumor formation. |
| Reactivity | Human |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 37.50 kDa |
| Recommended Dilutions | |
| Immunogen | PDLIM2 (NP_0676432, 1 aa ~ 352 aa) full-length human protein |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | FLJ34715, MYSTIQUE, SLIM |
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