| No | Size | Price | Availability | |
| ARP29760-11 | 50ul | 1500.00 | In Stock |  |
| ARP29760-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 29760 |
| Isotype: | / | Swiss Prot: | Q8WV28 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Reactivity | Human, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50.50 kDa |
| Recommended Dilutions | |
| Immunogen | BLNK (AAH189061, 1 aa ~ 456 aa) full-length human protein |
| Storage | Store at -20°C or lower in PBS(pH 7.4). Avoid freeze/thaw cycles. |
| Synonym | BASH, BLNK-S, LY57, MGC111051, SLP-65, SLP65 |
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